BDBM650446 US20240043427, Example 547

SMILES C[C@H](NC(=O)O[C@H]1CN(CC1(F)F)c1cc(nn2ccnc12)-c1c[nH]c(=O)[nH]c1=O)C(F)(F)F

InChI Key InChIKey=MMSNBRPMBQUUPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650446   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650446(US20240043427, Example 547)
Affinity DataIC50: 0.310nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent