BDBM650501 BDBM650509::US20240043427, Example 602

SMILES Fc1cnc2c(cc(nn12)-c1c[nH]c(=O)[nH]c1=O)[C@H]1C[C@@H]1c1ccc2cnn(CC(F)(F)F)c2n1

InChI Key InChIKey=MPFMXWWCWNKJDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650501   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650501(BDBM650509 | US20240043427, Example 602)
Affinity DataIC50: 0.370nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650501(BDBM650509 | US20240043427, Example 602)
Affinity DataIC50: 0.930nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent