BDBM650642 (2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-((2,6- dichlorophenyl)sulfonyl)-N-(4-methyl-3- (trifluoromethyl)phenyl)piperidine-3-carboxamide::US20240043439, Compound 20

SMILES Cc1ccc(NC(=O)[C@H]2CCCN([C@H]2c2ccc(NC3CCCC3)cc2)S(=O)(=O)c2c(Cl)cccc2Cl)cc1C(F)(F)F

InChI Key InChIKey=GHERBRFMMQSMDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650642   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650642((2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-((2,6- di...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650642((2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-((2,6- di...)
Affinity DataIC50: 1.00E+5nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent