BDBM650660 2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-5-hydroxy-N-(4-methyl-3-(trifluoromethyl)phenyl)piperidine-3-carboxamide::US20240043439, Compound 42

SMILES Cc1ccc(NC(=O)C2CC(O)CN(C2c2ccc(NC3CCCC3)cc2)C(=O)c2c(C)cccc2F)cc1C(F)(F)F

InChI Key InChIKey=GLFDHEVEPDJMNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650660   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650660(2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methy...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
US Patent