BDBM650760 (2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-((3,5- dimethylphenyl)sulfonyl)-N-(4-methyl-3- (trifluoromethyl)phenyl)piperidine-3-carboxamide::US20240043439, Compound 12

SMILES Cc1cc(C)cc(c1)S(=O)(=O)N1CCC[C@@H]([C@@H]1c1ccc(NC2CCCC2)cc1)C(=O)Nc1ccc(C)c(c1)C(F)(F)F

InChI Key InChIKey=VYQIHBILFJDIJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650760   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650760((2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-((3,5- di...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent