BDBM651015 15,18,21-trifluoro-2-[(2S)-2-methyl-4-(prop-2- enoyl)piperazin-1-yl]-6-(propan-2-yl)- 10,11,12,13-tetrahydro-4H-1,19- (ethanediylidene)pyrido[4,3-f]pyrimido[1,6- h][1,8,10]benzoxadiazacyclotridecin-4-one::US20240043448, Example 79

SMILES CC(C)c1nccc2CCCCOc3c(F)ccc(F)c3-c3nc4n(-c12)c(=O)nc(N1CCN(C[C@@H]1C)C(=O)C=C)c4cc3F

InChI Key InChIKey=AERODAPTMUATNO-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651015   

TargetGTPase KRas [2-169,G12C,C51S,C80L,C118S](Human sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM651015(15,18,21-trifluoro-2-[(2S)-2-methyl-4-(prop-2- eno...)
Affinity DataIC50:  2.60nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series in a 384-well low dead volume microplate (Labc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent