BDBM651113 US20240043470, Compound 1-66

SMILES FC(F)(F)CNC(=O)[C@@H]1Cc2cccc(Oc3cccc(C[C@H](N4CCCC4=O)C(=O)N[C@@H](CCN4CCC(F)(F)CC4)C(=O)N1)c3)c2

InChI Key InChIKey=ZKJJWKVXSWEVGP-QKDODKLFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651113   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM651113(US20240043470, Compound 1-66)
Affinity DataIC50: >1.00E+5nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM651113(US20240043470, Compound 1-66)
Affinity DataIC50:  140nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent