BDBM651229 1-{[2-({4-[(2S)-2-(5-chloropyridin-2-yl)-2-methyl-2H-1,3-benzodioxol-4-yl]piperidin-1-yl}methyl)-5-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]pyridin-3-yl]methyl}cyclopropane-1-carbonitrile ::US11897851, Compound 277

SMILES C[C@@]1(Oc2cccc(C3CCN(Cc4ncc(cc4CC4(CC4)C#N)-c4nnc([nH]4)C(F)(F)F)CC3)c2O1)c1ccc(Cl)cn1

InChI Key InChIKey=KPVJAIMORNCLCW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651229   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM651229(1-{[2-({4-[(2S)-2-(5-chloropyridin-2-yl)-2-methyl-...)
Affinity DataEC50:  0.0230nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent