BDBM651289 6-(2,5'-difluoro-2'-methyl[1,1'-biphenyl]-4-yl)-4,5-dihydropyridazin-3(2H)-one::US11897867, Example 57

SMILES Cc1ccc(F)cc1-c1ccc(cc1F)C1=NNC(=O)CC1

InChI Key InChIKey=REJUWQIONJTBCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651289   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
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US Patent
LigandPNGBDBM651289(US11897867, Example 57 | 6-(2,5'-difluoro-2'-methy...)
Affinity DataIC50: 60nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651289(US11897867, Example 57 | 6-(2,5'-difluoro-2'-methy...)
Affinity DataIC50: 180nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent