BDBM651331 2'-methyl-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)[1,1'-biphenyl]-4-carbonitrile::US11897867, Example 100

SMILES Cc1cc(ccc1-c1ccc(cc1)C#N)C1=NNC(=O)CC1

InChI Key InChIKey=HAMODGODIOOSAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651331   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
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US Patent
LigandPNGBDBM651331(US11897867, Example 100 | 2'-methyl-4'-(6-oxo-1,4,...)
Affinity DataIC50: 58nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651331(US11897867, Example 100 | 2'-methyl-4'-(6-oxo-1,4,...)
Affinity DataIC50: 59nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent