BDBM651365 GSK WO2018 092089, Example 129::US11897876, Comparator Example C::[1-[6-(5-Methyl-1,3,4-oxadiazol-2-yl)pyrimidin-4-yl]-4-piperidyl]-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]methanone

SMILES Cc1nnc(-c2cc(N3CCC(C(=O)N4N=CC[C@H]4c4ccccc4)CC3)ncn2)o1

InChI Key InChIKey=SFPXMZKKQUMNPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651365   

LigandChemical structure of BindingDB Monomer ID 651365BDBM651365(GSK WO2018 092089, Example 129 | [1-[6-(5-Methyl-1...)
Affinity DataIC50: 37nMAssay Description:In detail, 2 μl recombinantly produced hRIPK1 (aa 1-375) fusion protein (end concentration 3.6 μg/ml) and 2 μl compound (end concentra...More data for this Ligand-Target Pair
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Date in BDB:
4/18/2024
Entry Details
US Patent