BDBM651391 (E)-2-(1-((4-ethoxy-3-(6-((hydroxyimino)methyl)-5-methyl-4-oxo-7-propyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl)sulfonyl)piperidin-4-yl)ethyl nitrate::US11897890, Compound lam

SMILES CCCc1c(/C=N/O)c(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(CCO[N+](=O)[O-])CC4)ccc3OCC)nn12

InChI Key InChIKey=MMAIEMLNBMNQSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651391   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 651391BDBM651391((E)-2-(1-((4-ethoxy-3-(6-((hydroxyimino)methyl)-5-...)
Affinity DataIC50: 66nMAssay Description:Experimental protocol: The test compound, i.e the compound of the present invention, reference compound or water (control) are added to a buffer cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
US Patent