BDBM651754 N-(2-methoxyethyl)-1- methyl-2-((6-(2,2,2- trifluoroethoxy)benzo- [d]oxazol-2-yl)amino)- 1H-benzo[d]imidazole- 5-carboxamide::US20240051952, Example 99

SMILES COCCNC(=O)c1ccc2n(C)c(Nc3nc4ccc(OCC(F)(F)F)cc4o3)nc2c1

InChI Key InChIKey=QZVLAWMTHUDPAC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651754   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651754(US20240051952, Example 99 | N-(2-methoxyethyl)-1- ...)
Affinity DataEC50:  920nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent