BDBM651755 N-(2-hydroxyethyl)-1- methyl-2-((6-(2,2,2- trifluoroethoxy)benzo- [d]oxazol-2-yl)amino)- 1H-benzo[d]imidazole- 5-carboxamide::US20240051952, Example 100

SMILES Cn1c(Nc2nc3ccc(OCC(F)(F)F)cc3o2)nc2cc(ccc12)C(=O)NCCO

InChI Key InChIKey=INAYNLBXXNANRB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651755   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651755(US20240051952, Example 100 | N-(2-hydroxyethyl)-1-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent