BDBM651800 6-chloro-5-methoxy-2-(5- methoxy-4H-1,2,4-triazol-3- yl)-3-(1H-pyrazol-4-yl)-1H- pyrrolo[3,2-b]pyridine::US20240051954, Example 12

SMILES COc1nnc(-c2[nH]c3cc(Cl)c(OC)nc3c2-c2cn[nH]c2)[nH]1

InChI Key InChIKey=CQGGIZNHQZXSAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651800   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 651800BDBM651800(US20240051954, Example 12 | 6-chloro-5-methoxy-2-(...)
Affinity DataIC50: 333nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
US Patent