BDBM651821 6-chloro-2-(5-fluoro-4H-1,2,4- triazol-3-yl)-3-(1H-imidazol-1- yl)-5-methoxy-1-methyl-1H- pyrrolo[3,2-b]pyridine::US20240051954, Example 33

SMILES COc1nc2c(c(-c3nnc(F)[nH]3)n(C)c2cc1Cl)-n1ccnc1

InChI Key InChIKey=RZWLEFUGFDVWFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651821   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651821(6-chloro-2-(5-fluoro-4H-1,2,4- triazol-3-yl)-3-(1H...)
Affinity DataIC50:  332nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent