BDBM651833 6-chloro-3-(1H-imidazol-1-yl)- 5-methoxy-1-methyl-2-(5- (trifluoromethyl)-4H-1,2,4- triazol-3-yl)-1H-pyrrolo[3,2- b]pyridine::US20240051954, Example 45

SMILES COc1nc2c(c(-c3nnc([nH]3)C(F)(F)F)n(C)c2cc1Cl)-n1ccnc1

InChI Key InChIKey=LLQGUURJMXHPFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651833   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651833(6-chloro-3-(1H-imidazol-1-yl)- 5-methoxy-1-methyl-...)
Affinity DataIC50:  384nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent