BDBM652389 US20240059676, Compound ZB-H-31

SMILES Oc1cnc2n(ccc2c1)-c1c(Cl)cc(cc1Cl)-n1nc(C#N)c(=O)[nH]c1=O

InChI Key InChIKey=VDMLUYAVLNHXCA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652389   

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM652389(US20240059676, Compound ZB-H-31)
Affinity DataEC50:  1.10E+3nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM652389(US20240059676, Compound ZB-H-31)
Affinity DataEC50:  3.10E+3nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent