BDBM652397 US20240059676, Compound ZB-H-45

SMILES Clc1cc(NC(=O)c2noc(=O)[nH]2)cc(Cl)c1-n1ccc2n(C3CCCC3)c(=O)ccc12

InChI Key InChIKey=MSIRJCGRQSAEGC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652397   

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM652397(US20240059676, Compound ZB-H-45)
Affinity DataEC50:  50nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM652397(US20240059676, Compound ZB-H-45)
Affinity DataEC50:  500nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent