BDBM652415 US20240059682, Example 22

SMILES CC(F)(F)c1nc2ccc(Oc3c(Cl)cc(cc3Cl)-n3nc(C#N)c(=O)[nH]c3=O)cc2n1C1(C)CC1

InChI Key InChIKey=ARXRUFRBDBIBDA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652415   

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652415(US20240059682, Example 22)
Affinity DataEC50:  270nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652415(US20240059682, Example 22)
Affinity DataEC50:  70nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent