BDBM652418 US20240059682, Example 25

SMILES CC1(CC1)n1cnc2ccc(Oc3c(Cl)cc(cc3Cl)-n3ncc(=O)[nH]c3=O)cc12

InChI Key InChIKey=CHGSISXOSKUHIZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652418   

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652418(US20240059682, Example 25)
Affinity DataEC50:  20nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652418(US20240059682, Example 25)
Affinity DataEC50:  110nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent