BDBM653230 US20240059703, Example 14-1

SMILES CC1(C)[C@H]2Cc3c(nc(N4CCC5(CNC5)C4)c(F)c3-c3cc(O)cc4ccccc34)[C@@H]1C2

InChI Key InChIKey=AOWANRFNYPQXTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653230   

LigandChemical structure of BindingDB Monomer ID 653230BDBM653230(US20240059703, Example 14-1)
Affinity DataIC50: 18nMAssay Description:Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent