BDBM653552 3-(7'-oxo-3',4',7',9'-tetrahydro- 8'H-spiro[piperidine-4,2'- pyrano[2,3-e]isoindol]-8'- yl)piperidine-2,6-dione::US20240059704, Compound A2

SMILES O=C1N(Cc2c1ccc1CCC3(CCNCC3)Oc21)C1CCC(=O)NC1=O

InChI Key InChIKey=LBUSZCRLDPVESA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653552   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandPNGBDBM653552(3-(7'-oxo-3',4',7',9'-tetrahydro- 8'H-spiro[piperi...)
Affinity DataIC50:  620nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent