BDBM653555 (S)-3-(7′-oxo-7′,9′-dihydro-2′H,8′H-spiro[piperidine-4,3′-[1,4]dioxino[2,3-e]isoindol]-8′-yl)piperidine-2,6-dione::US20240059704, Compound B1

SMILES O=C1N(Cc2c1ccc1OC3(CCNCC3)COc21)[C@H]1CCC(=O)NC1=O

InChI Key InChIKey=MRTAHKBGZKGBRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653555   

TargetProtein cereblon(Human)
University of Michigan

US Patent
LigandPNGBDBM653555(US20240059704, Compound B1 | (S)-3-(7′-oxo-7...)
Affinity DataIC50: 330nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent