BDBM653909 N-(6-isopropylbenzothiazole-2-yl)-4-morpholinobenzamide::US11912678, Compound 10

SMILES CC(C)Oc1ccc2nc(NC(=O)c3ccc(cc3)N3CCOCC3)sc2c1

InChI Key InChIKey=ZWCZXXDAFKVNEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 653909   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM653909(N-(6-isopropylbenzothiazole-2-yl)-4-morpholinobenz...)
Affinity DataIC50: 1.17E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM653909(N-(6-isopropylbenzothiazole-2-yl)-4-morpholinobenz...)
Affinity DataIC50: 1.95E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent