BDBM653942 US11912682, Compound 40

SMILES CN1CCC(COc2cc(Cl)cc(NC(=O)OCc3ccc4CN(C5CCC(=O)NC5=O)C(=O)c4c3)c2)C1

InChI Key InChIKey=GRLIWPLFKQBCAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653942   

TargetProtein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandPNGBDBM653942(US11912682, Compound 40)
Affinity DataIC50: 500nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1-[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent