BDBM654407 3-(1-cyclopentyl-1H- benzo[d][1,2,3]triazol-5-yl)-5-(2- (methylthio)phenyl)-1,2,4-oxadiazole::US11912693, Compound 16

SMILES CSc1ccccc1-c1nc(no1)-c1ccc2n(nnc2c1)C1CCCC1

InChI Key InChIKey=LQVBMLOQBXQGSY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654407   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654407(US11912693, Compound 16 | 3-(1-cyclopentyl-1H- ben...)
Affinity DataEC50: >316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654407(US11912693, Compound 16 | 3-(1-cyclopentyl-1H- ben...)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent