BDBM654818 N-[(4E)-2,2-diethyl-6-[3-(pyridin-3- yl)-1,2,4-oxadiazol-5-yl]-3,4-dihydro- 2H-1-benzopyran-4- ylidene]hydroxylamine::US11912693, Compound 431

SMILES CCC1(CC)C\C(=N/O)c2cc(ccc2O1)-c1nc(no1)-c1cccnc1

InChI Key InChIKey=LACKBTZKOURGLK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654818   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654818(US11912693, Compound 431 | N-[(4E)-2,2-diethyl-6-[...)
Affinity DataEC50: >316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654818(US11912693, Compound 431 | N-[(4E)-2,2-diethyl-6-[...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent