BDBM654835 2-(1-isobutyl-1H- benzo[d][1,2,3]triazol-5-yl)-6- methylbenzo[d]oxazole::US11912693, Compound 448

SMILES CC(C)Cn1nnc2cc(ccc12)-c1nc2ccc(C)cc2o1

InChI Key InChIKey=OVZFKBPVOIFYOV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654835   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654835(US11912693, Compound 448 | 2-(1-isobutyl-1H- benzo...)
Affinity DataEC50: >316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654835(US11912693, Compound 448 | 2-(1-isobutyl-1H- benzo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent