BDBM654841 7-bromo-2-(1-isobutyl-1H- benzo[d][1,2,3]triazol-5- yl)benzo[d]oxazole::US11912693, Compound 454

SMILES CC(C)Cn1nnc2cc(ccc12)-c1nc2cccc(Br)c2o1

InChI Key InChIKey=ADBSQEFZPLLKSZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654841   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654841(US11912693, Compound 454 | 7-bromo-2-(1-isobutyl-1...)
Affinity DataEC50: <316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654841(US11912693, Compound 454 | 7-bromo-2-(1-isobutyl-1...)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent