BDBM654845 N-(2-{2-[1-(propan-2-yl)-1H-1,2,3- benzotriazol-5-yl]-1,3-oxazol-4- yl}phenyl)acetamide::US11912693, Compound 458

SMILES CC(C)n1nnc2cc(ccc12)-c1nc(co1)-c1ccccc1NC(C)=O

InChI Key InChIKey=AQSGVRYJUNCGPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654845   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654845(US11912693, Compound 458 | N-(2-{2-[1-(propan-2-yl...)
Affinity DataEC50: >316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandPNGBDBM654845(US11912693, Compound 458 | N-(2-{2-[1-(propan-2-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent