BDBM656036 2-cyclopropanecarbonyl-6-{[1-methyl-4-(6-methylpyridin-3-yl)-1H-1,2,3-triazol-5-yl]methoxy}-1,2,3,4-tetrahydro-2,7-naphthyridine::US12637455, Example 65::US20240067637, Example 65

SMILES Cc1ccc(cn1)-c1nnn(C)c1COc1cc2CCN(Cc2cn1)C(=O)C1CC1

InChI Key InChIKey=KLYSOMCPBQOCIX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 656036   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 656036BDBM656036(2-cyclopropanecarbonyl-6-{[1-methyl-4-(6-methylpyr...)
Affinity DataKi:  52nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 656036BDBM656036(2-cyclopropanecarbonyl-6-{[1-methyl-4-(6-methylpyr...)
Affinity DataKi:  52nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2026
Entry Details
US Patent