BDBM656368 N-(2-Phenyl-2,3-dihydro-1-benzofuran-6-yl)-N′-[(pyridin-4-yl)methyl]urea::US11918568, Example 51

SMILES O=C(NCc1ccncc1)Nc1ccc2CC(Oc2c1)c1ccccc1

InChI Key InChIKey=BAIRTYQJAXROJI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656368   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM656368(N-(2-Phenyl-2,3-dihydro-1-benzofuran-6-yl)-N′...)
Affinity DataEC50:  120nMAssay Description:The NAMPT enzyme assay was conducted in accordance with the method of Formentini et al. (Formentini L. et al., Biochemical Pharmacology 77 (2009) 161...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent