BDBM656369 N-[2-(3-Methoxyphenyl)-2,3-dihydro-1-benzofuran-6-yl]-N′-[(pyridin-4-yl)methyl]urea::US11918568, Example 52

SMILES COc1cccc(c1)C1Cc2ccc(NC(=O)NCc3ccncc3)cc2O1

InChI Key InChIKey=FDHLKQOIXNYNEL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656369   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM656369(N-[2-(3-Methoxyphenyl)-2,3-dihydro-1-benzofuran-6-...)
Affinity DataEC50:  80nMAssay Description:The NAMPT enzyme assay was conducted in accordance with the method of Formentini et al. (Formentini L. et al., Biochemical Pharmacology 77 (2009) 161...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent