BDBM656370 N-[(2S*,3S*)-2-(3-Methoxyphenyl)-3-methyl-2,3-dihydro-1-benzofuran-6-yl]-N′-[(pyridin-4-yl)methyl]urea::US11918568, Example 53

SMILES COc1cccc(c1)[C@H]1Oc2cc(NC(=O)NCc3ccncc3)ccc2[C@@H]1C

InChI Key InChIKey=FRMVQHOUGSWHIT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656370   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM656370(N-[(2S*,3S*)-2-(3-Methoxyphenyl)-3-methyl-2,3-dihy...)
Affinity DataEC50:  80nMAssay Description:The NAMPT enzyme assay was conducted in accordance with the method of Formentini et al. (Formentini L. et al., Biochemical Pharmacology 77 (2009) 161...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent