BDBM656466 US11919855, Name NUCC-0226237

SMILES COC(=O)c1ccccc1CN1CC(CCC1=O)NC(=O)c1cc(ccc1O)C(F)(F)F

InChI Key InChIKey=HWABPMLNPZLMRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656466   

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656466(US11919855, Name NUCC-0226237)
Affinity DataIC50: 5.50E+3nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent