BDBM656492 (2R,3S,4S,5R)-4-[[3-[2-(difluoromethoxy)-3,4-difluoro-phenyl]-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carbonyl]amino]-1-oxido-pyridin-1-ium-2-carboxamide ::US11919887, Compound 18

SMILES C[C@H]1[C@H]([C@@H](O[C@@]1(C)C(F)(F)F)C(=O)Nc1cc[n+]([O-])c(c1)C(N)=O)c1ccc(F)c(F)c1OC(F)F

InChI Key InChIKey=YGHDRMYCIVDFBL-URSPGPRKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656492   

TargetSodium channel protein type 5 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM656492((2R,3S,4S,5R)-4-[[3-[2-(difluoromethoxy)-3,4-diflu...)
Affinity DataIC50: <10nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent