BDBM656964 5-((2-ethynyl- 5-(prop-1-en- 2-yl)pyridin- 4-yl)oxy) pyrimidine-2,4- diamine::US11919918, Compound C215

SMILES CC(=C)c1cnc(cc1Oc1cnc(N)nc1N)C#C

InChI Key InChIKey=OTAPLTATGFXASH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 656964   

TargetP2X purinoceptor 3(Human)
Beijing Tide Pharmaceutical Co.

US Patent
LigandPNGBDBM656964(5-((2-ethynyl- 5-(prop-1-en- 2-yl)pyridin- 4-yl)ox...)
Affinity DataIC50: 88.2nMAssay Description:Cells were seeded into a poly-D-lysine-coated 384-well cell culture plate (Corning) at a density of 11,000 cells/well/25 μL of cell inoculation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
Beijing Tide Pharmaceutical Co.

US Patent
LigandPNGBDBM656964(5-((2-ethynyl- 5-(prop-1-en- 2-yl)pyridin- 4-yl)ox...)
Affinity DataIC50: 194nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent