BDBM656977 5-((2-bromo-5- isopropylpyridin- 4-yl)oxy)-N2- cyclopropyl- pyrimidine-2,4- diamine::US11919918, Compound C238

SMILES CC(C)c1cnc(Br)cc1Oc1cnc(NC2CC2)nc1N

InChI Key InChIKey=PZEMWICRKUFKQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 656977   

TargetP2X purinoceptor 3(Human)
Beijing Tide Pharmaceutical Co.

US Patent
LigandPNGBDBM656977(5-((2-bromo-5- isopropylpyridin- 4-yl)oxy)-N2- cyc...)
Affinity DataIC50: 104nMAssay Description:Cells were seeded into a poly-D-lysine-coated 384-well cell culture plate (Corning) at a density of 11,000 cells/well/25 μL of cell inoculation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
Beijing Tide Pharmaceutical Co.

US Patent
LigandPNGBDBM656977(5-((2-bromo-5- isopropylpyridin- 4-yl)oxy)-N2- cyc...)
Affinity DataIC50: 206nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent