BDBM657040 US11926614, Example 21

SMILES Clc1ccccc1-n1c(nnc1C12CC(C1)(C2)NC(=O)c1ccnc2cccnc12)-c1ccncn1

InChI Key InChIKey=NAJKQXORVFTZPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657040   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandPNGBDBM657040(US11926614, Example 21)
Affinity DataIC50: 1.80nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent