BDBM657052 2-(3-(5-Amino-6-(isothiazol-4-yl)pyrazin-2- yl)-4-methylphenyl)-3,3,3-trifluoropropane- 1,2-diol, trifluoroacetate salt (single enantiomer isolated, believed to be (S)-2-(3- (5-Amino-6-(isothiazol-4-yl)pyrazin-2-yl)-4- methylphenyl)-3,3,3-trifluoropropane-1,2- diol)::2-(3-(5-Amino-6-(isothiazol-4-yl)pyrazin-2-yl)-4-methylphenyl)-3,3,3-trifluoropropane-1,2-diol::US11926616, Example 5
SMILES Cc1ccc(cc1-c1cnc(N)c(n1)-c1cnsc1)C(O)(CO)C(F)(F)F
InChI Key InChIKey=HHLVSPKMPXSCLE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 657052
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair