BDBM657162 (S)-3-Amino-N-(4- hydroxybicyclo[2.2.1]heptan-1-yl)-6-(2- (methyl-d3)-5-(1,1,1-trifluoro-2,3- dihydroxypropan-2-yl)phenyl)pyrazine-2- carboxamide, trifluoroacetate salt (single enantiomer)::(S)-3-Amino-N-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-6-(2-(methyl-d3)-5-(1,1,1-trifluoro-2,3-dihydroxypropan-2-yl)phenyl)pyrazine-2-carboxamid::US11926616, Example 35
SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NC12CCC(O)(CC1)C2)[C@](O)(CO)C(F)(F)F
InChI Key InChIKey=SWHDEXCHFGHVHN-XVAXZDLZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 657162
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair