BDBM657162 (S)-3-Amino-N-(4- hydroxybicyclo[2.2.1]heptan-1-yl)-6-(2- (methyl-d3)-5-(1,1,1-trifluoro-2,3- dihydroxypropan-2-yl)phenyl)pyrazine-2- carboxamide, trifluoroacetate salt (single enantiomer)::(S)-3-Amino-N-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-6-(2-(methyl-d3)-5-(1,1,1-trifluoro-2,3-dihydroxypropan-2-yl)phenyl)pyrazine-2-carboxamid::US11926616, Example 35

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NC12CCC(O)(CC1)C2)[C@](O)(CO)C(F)(F)F

InChI Key InChIKey=SWHDEXCHFGHVHN-XVAXZDLZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657162   

LigandPNGBDBM657162((S)-3-Amino-N-(4- hydroxybicyclo[2.2.1]heptan-1-yl...)
Affinity DataIC50: <100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM657162((S)-3-Amino-N-(4- hydroxybicyclo[2.2.1]heptan-1-yl...)
Affinity DataIC50: <100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent