BDBM657180 3-amino-6-(5-((S)-1,1-difluoro-2,3- dihydroxypropan-2-yl)-2-methylphenyl)-N- (3-methyltetrahydrofuran-3-yl)pyrazine-2- carboxamide, trifluoroacetate salt (mixture of two diastereomers)::3-amino-6-(5-((S)-1,1-difluoro-2,3-dihydroxypropan-2-yl)-2-methylphenyl)-N-(3-methyltetrahydrofuran-3-yl)pyrazine-2-carboxamide::US11926616, Example 47
SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NC1(C)CCOC1)[C@](O)(CO)C(F)F
InChI Key InChIKey=CSRLWDDXBQWWMU-GFOWMXPYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 657180
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair