BDBM657180 3-amino-6-(5-((S)-1,1-difluoro-2,3- dihydroxypropan-2-yl)-2-methylphenyl)-N- (3-methyltetrahydrofuran-3-yl)pyrazine-2- carboxamide, trifluoroacetate salt (mixture of two diastereomers)::3-amino-6-(5-((S)-1,1-difluoro-2,3-dihydroxypropan-2-yl)-2-methylphenyl)-N-(3-methyltetrahydrofuran-3-yl)pyrazine-2-carboxamide::US11926616, Example 47

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NC1(C)CCOC1)[C@](O)(CO)C(F)F

InChI Key InChIKey=CSRLWDDXBQWWMU-GFOWMXPYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657180   

LigandPNGBDBM657180(3-amino-6-(5-((S)-1,1-difluoro-2,3- dihydroxypropa...)
Affinity DataIC50: <100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM657180(3-amino-6-(5-((S)-1,1-difluoro-2,3- dihydroxypropa...)
Affinity DataIC50: <100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent