BDBM657320 US11926628, Example 137

SMILES Cc1nnc2nc(N3CCOCc4c(cccc34)C#Cc3cnn(C)c3)c3ccc(nc3n12)C(F)(F)F

InChI Key InChIKey=CVPMAMCPKQTPFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657320   

TargetDiacylglycerol kinase alpha(Human)
Gilead Sciences

US Patent
LigandPNGBDBM657320(US11926628, Example 137)
Affinity DataIC50: 8.38nMAssay Description:Ten nanoliters of test compound dissolved in DMSO at various concentrations were dispensed into a 384-well low volume nonbinding service white plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent