BDBM657321 US11926628, Example 138

SMILES Cc1nnc2nc(N3CCOCc4c(cccc34)C#CC(C)(C)C#N)c3ccc(nc3n12)C(F)(F)F

InChI Key InChIKey=PZYIIJISJSEWKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657321   

TargetDiacylglycerol kinase alpha(Human)
Gilead Sciences

US Patent
LigandPNGBDBM657321(US11926628, Example 138)
Affinity DataIC50: 6.56nMAssay Description:Ten nanoliters of test compound dissolved in DMSO at various concentrations were dispensed into a 384-well low volume nonbinding service white plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent