BDBM657647 6,7-dimethoxy-2-methyl-N-[1-(4-{2-[(methylamino)methyl]phenyl}thiophen-2-yl)ethyl]quinazolin-4-amine, Enantiomer 1::US20240083857, Example 326

SMILES CNCc1ccccc1c4csc(C(C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c4

InChI Key InChIKey=WEGLOYDTDILXDA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657647   

TargetGTPase KRas(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 657647BDBM657647(6,7-dimethoxy-2-methyl-N-[1-(4-{2-[(methylamino)me...)
Affinity DataIC50: 50nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed