BDBM658087 US20240083897, Compound 38

SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(-c2ccc3c(ncn3c2)-c2ncc[nH]2)c1C#N

InChI Key InChIKey=KKBKAXVTDXOIEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658087   

TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658087(US20240083897, Compound 38)
Affinity DataIC50: <50nMAssay Description:GCN2 protein was obtained from Carna Biosciences (cat #05-153). The protein was diluted in assay buffer (ThermoFisher Scientific, #PV6135), 2 mM dith...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent