BDBM658257 US20240083900, Example 2

SMILES Cn1cc(cn1)-c1cn2nccc2c(OC2CCN(CC2)C(=O)C=C)n1

InChI Key InChIKey=VHRPNFQXOODJOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 658257   

TargetTyrosine-protein kinase BTK(Human)
Biogen Research and Development

Curated by ChEMBL
LigandPNGBDBM658257(US20240083900, Example 2)
Affinity DataIC50: 63nMAssay Description:Inhibition of BTK (unknown origin) using fluorescein labeled polyGAT peptide substrate incubated for 30 mins in presence of ATP by time-resolved fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Biogen Research and Development

Curated by ChEMBL
LigandPNGBDBM658257(US20240083900, Example 2)
Affinity DataIC50: 505nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent