BDBM658464 1-((1R,3R,5S)-3-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)-6-azabicyclo[3.2.1]octan-6-yl)prop-2-en-1-one and 1-((1S,3S,5R)-3-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)-6-azabicyclo[3.2.1]octan-6-yl)prop-2-en-1-one::US20240083900, Example 167

SMILES Cn1cc(cn1)-c1cn2nccc2c(O[C@@H]2C[C@H]3C[C@@H](C2)N(C3)C(=O)C=C)n1

InChI Key InChIKey=SERKKWPCLAUPDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658464   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658464(US20240083900, Example 167 | 1-((1R,3R,5S)-3-((6-(...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
US Patent