BDBM658467 N-methyl-N-((1S,3R)-3-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)cyclohexyl)acrylamide and N-methyl-N-((1R,3S)-3-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)cyclohexyl)acrylamide::US20240083900, Example 175

SMILES CN([C@H]1CCC[C@H](C1)Oc1nc(cn2nccc12)-c1cnn(C)c1)C(=O)C=C

InChI Key InChIKey=NYWCWYYJWLUGRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658467   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658467(US20240083900, Example 175 | N-methyl-N-((1S,3R)-3...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
US Patent